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Research

Our lab studies the properties of various types of neurons and synapses in the subiculum, the prefrontal cortex and the lateral habenula

These diverse brain regions are known to be linked to multiple diseases such as Alzheimer’s disease, depression, and temporal lobe epilepsy.

We focus on how different populations of neurons communicate with each other, both locally and via long-range connections. By using optogenetics, electrophysiology and anatomical methods we aim to characterize and manipulate specific subpopulations of neurons and their connections to redefine the neuronal wiring diagram.

We also examine how neurons and synapses are regulated by neuromodulators, and how pharmacological compounds interact with synaptic receptors expressed in subsets of excitatory and inhibitory neurons.

 

 

 

 

Optogenetic circuit mapping

Immunohistochemistry

Pharmacology

 

 

 

Funding/Support

We are grateful to our funders.

 

 

 

 

 

 

 

 

Research